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TurboMice™ - Preclinical Frontier by VelogoGene

GDF15: A Stress Factor Evolving from a "Cachexia Signal" to a Novel Target in Tumour Immunity and Metabolism
In patients with advanced cancer, cachexia — a state characterised by severe weight loss, appetite loss...
What Is Progerin? LMNA‑Mutant Progeria Mice — A Potential “Gold Standard” for Aging Research
I. From Gene Editing to Aging‑Related Phenotypes: Why Choose LMNA?Gene‑edited mice employ molecular‑biology,...
APOE & Related Mouse Models: A Bridge From Lipid Metabolism to Precision Treatment of AD
Apolipoprotein E (APOE) is a star target in lipid‑metabolism and neurodegenerative‑disease research....
Moderna Phase‑3 Positive Result Ignites mRNA Cancer Vaccine: Unpacking the "Golden‑Partner" Gene‑Edited Mouse Models Behind mRNA Tumor Vaccines
On August 19, 2026, blockbuster news swept the biotech community: Moderna and Merck announced that Intismeran...
Preclinical Frontier Aug 2026 | Hotbeds of Innovative Drug Discovery — Interpretation of 11 First-in-Class Targets Disclosed in Recent Nature Literature
In July 2026, Nature Reviews Drug Discovery published the article Novel drug targets in 2025. According...
From Glycemia-Inducing Culprit to New Star of Metabolic Therapy: Mechanism Analysis & Humanized Models of GCGR Target
The global population living with type 2 diabetes mellitus (T2DM) has reached 590 million, and the figure...
TIGIT: A Master Regulator Balancing Tumor Immunity and Autoimmunity
In 2024, major pharmaceutical corporations heavily invested in the TIGIT (T cell immunoreceptor with...
PCSK9: Core Regulator of Cholesterol Metabolism & Novel Anti-Tumor Target
On November 7–10, 2025, the American Heart Association (AHA) Scientific Sessions was held in New Orleans,...
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