VeloGene - TurboMice™

F0 Homozygous Mouse Models

2× Faster Than Traditional Approaches

KO · cKO · KI · Humanized · Point Mutation · Transgenic

Custom Models

Strains in Stock

Research Service

Custom Services

Humanize

Multi-Site Customization on Same Chromosome
Minimum Genetic Drift

KO homozygous with identical alleles
Homozygous mice: as little as 3 months

Rosa 26/H11 KI
High-efficiency long-range knock-in （~100kb）
Homozygous mice: as little as 3 months

cKO

F0 100% targeted Gene^flox/flox ; Cre⁺
F0 models in 4–6 months via tetraploid ESC engineering.

Point Mutation

Single-Chromosome Multiplex Editing
ESC homologous recombination, precise introduction of target mutations

What is TurboMice™？

TurboMice™ by Dr. Wu Guangming redefines animal model generation through Tetraploid Complementation Technology (TCT) and precision stem cell engineering. Bypassing traditional multi-generational breeding and chimeric phases, the platform drives edited Embryonic Stem Cells (ESCs) directly into fully homozygous cohorts.

Accelerated Timelines: 45-day turnaround from cell line validation to functional models; full in vivo readiness in 3 to 5 months.
Uncompromising Precision: Direct homozygous development ensures exceptional genetic consistency and eliminates off-target risks common in standard CRISPR workflows.
Global Enterprise Grade: SPF-grade genetically engineered mouse models and end-to-end technical support for elite research centers and biopharmaceutical enterprises worldwide.

About VeloGene Biotechnology

As a fully-owned subsidiary of MingCeler Biotech, VeloGene Biotechnology delivers custom, SPF-grade genetically engineered mouse models to multinational pharmaceutical firms and global research labs. Powered by MingCeler's game-changing TurboMice™ tetraploid complementation technology, we eliminate slow chimera breeding cycles to deliver fully homozygous mouse strains in just 2 to 5 months, dramatically accelerating preclinical research in rare diseases, oncology, and gene therapy.