The Next Generation of Mouse Model Preparation Platform
- 4-Week Delivery: World’s fastest custom mouse model development.
- TurboMice™ Tech: Proprietary high-efficiency gene-editing platform.
- Full Capabilities: Expert conditional knockouts, knock-ins, and humanized models.
- Validated Quality: Guaranteed high precision and model viability.
VeloGene Biotechnology
Knockout (KO) Mouse
for Research
From Cell to Mice by TurboMice™
- AAALAC
- ISO
- F0 Direct Usability: Homozygous mice ready for experiments instantly.
- 2–4 Month Delivery: 2× faster than the traditional 6–12 month timeline.
- Minimum Genetic Drift: Clone-level uniformity with absolute background consistency.
- IP Ownership: Strict fee-for-service model with absolute protection and no third-party resale.
- 2-Year Free ESC Banking: Effortless batch re-ordering in just 2 months.
- SPF Level Delivery From Door to Door
Get Your Project Evaluated by Our Scientist for Free
Or contact us here!
* Get a free, no-obligation feasibility assessment for your mouse project.
* All project information shared is strictly confidential, and your IP rights are fully protected.
Our team will respond within 24 working hours. We will not make unsolicited phone calls.
How Long it Takes to Get My Lab-Ready F0 Knockout(KO) Mice?
The next generation of mouse model preparation platform. By using tetraploid complementation technology, TurboMice™ allows us to shorten the time to 2-4 months. 2× faster than the traditional 6–12 month workflow.
2 - 4 Weeks→
Designing & Targeting Vector Constructing
2 - 4 Weeks→
Cell Editing & Screening
3 - 4 Weeks→
Tetraploid Mouse Producing
3 Weeks→
Weaned & Ready to Transport
Total:
2-4 Months
SPF level stable delivery from door to door
Re-ordering Mice in the Same Gene in 45 Days
by TurboMice™ ES Banking Technology
Leveraging advanced sperm cryopreservation, purification, and rederivation, we help you bypass traditional breeding bottlenecks. Whether dealing with limited male mice, pathogen contamination risks, or mating failures, our technology allows you to repeatedly obtain genetically identical, pathogen-free mouse cohorts with uniform ages in just about 45 days—saving time, cost, and animal housing space while securing your valuable genetic resources.
How to Get my
Knockout (KO)
Mouse Model?
We will determine the best approach for your desired knockout mouse model base on your requirements.
Send Your Inquiry
Before we start, you can start by submitting your inquiry form or talk to us on our Whatsapp and tell us what you need!
Solution Design
We will reply to you as soon as possible and send you a quote!
TurboMicing
We will get hands on your project.
Get your Ready to Use f0 Mice!
Our f0 homozygous mice will ship to you and lab-ready!
Full Qualification
VeloGene Biotechnology Shares the Qualifications of Its Parent Company - MingCeler Biotech
Including AAALAC, ISO, and China Laboratory Animal Production License
Clients Across the Continents
Our Clients Are Located Throughout the Asia Pacific, North America, and Europe with Seamless Global Delivery
Backed by our robust global delivery capabilities extending to clients in South Korea, the US, Germany, Sweden, and beyond, our reliable logistics and seamless customs compliance serve as your strongest guarantee, ensuring a stable, secure door-to-door journey from our facility straight to your lab using custom-built transport cages that fully comply with animal welfare standards, strict SPF-grade requirements, and multi-country import-export quarantine regulations for smooth customs clearance worldwide.
Client Cases
Scroll Down to See Technical Details on VeloGene Biotechnology's
Knockout Mouse Model Technical Details
Comparison, Advantages and FAQ
VeloGene Biotechnology Knockout Mouse Model Customize Service
F0 "Founder" Ready - to -Use
Knockout mice are engineered mammalian models in which a targeted gene is deleted or functionally inactivated to study the systemic consequences of its loss. By disrupting specific gene functions, these models allow researchers to investigate physiological, behavioral, and disease-related pathways, providing critical insights into human gene function and the pathogenesis of genetic disorders.
- Targeted Gene Disruption: Eliminates or inactivates specific genes to study the resulting phenotypic effects.
- Comprehensive Phenotypic Characterization: Enables the investigation of physiological, behavioral, and disease-related consequences caused by gene loss.
- Translational Insights: Provides critical understanding of human gene functions and the underlying mechanisms of genetic disorders.
What are knockout mice used for?
Knockout mouse models serve as indispensable tools for elucidating gene function and investigating the roles of specific genes in physiological and disease contexts.
To explore research leveraging mouse models in depth, visit our dedicated research section featuring publications and case studies.
Studying Gene Function
Functional gene deletion (“loss of function”) represents a fundamental genetic approach for investigating gene roles. This methodology entails comparative analysis between genetically modified knockout models and wild-type mice.
Human Disease Research with Knockout Mouse Models
Knockout mouse models serve as pivotal tools in human disease research. These models have significantly advanced our understanding of disease pathogenesis across multiple therapeutic areas, including:
- Oncology & Metabolic Disorders: Cancer, diabetes, obesity
- Cardiovascular & Inflammatory Diseases: Heart disease, arthritis
- Neurological Conditions: Neurodegenerative diseases
By generating knockout models targeting genes implicated in specific human disorders, researchers can:
- Investigate gene-disease relationships through controlled deletion
- Track disease progression dynamics across developmental stages
- Identify potential therapeutic intervention points
Guarantee
Mingceler provides the industry’s most robust guarantee: successful generation of genetically engineered knockout mice. Should we fail to deliver animals with the specified genotype, the client’s service fee will be fully refunded*.
Given the inherent complexity of biological systems, genetic modifications may not yield anticipated phenotypic outcomes. Mingceler’s guarantee strictly pertains to the development of animals possessing the genotype specified in the contract, with an accuracy of 100% at the DNA level, not the particular biological outcome,such as:
- Gene transcription levels
- Protein/RNA functionality
- Organism-level biological phenotype
*Exclusions apply for genetic modifications that severely compromise viability, morbidity, or fertility due to intrinsic biological constraints.
How to get your mice?
Send Your Inquiry
Before we start, you can start by submitting your inquiry form or talk to us on our Whatsapp and tell us what you need!
Solution Design
We will reply to you as soon as possible and send you a quote!
TurboMicing
We will get hands on your project.
Get your Ready to Use f0 Mice!
Our f0 homozygous mice will ship to you and lab-ready!
Related Products
IP Assurance
At VeloGene, we operate on a strict fee-for-service model. All intellectual property (IP) and materials created for your project are 100% yours. We take every measure to safeguard your IP, ensuring no vectors, ES cells, or mouse lines are retained or resold to third parties. This way, you can focus on your research with complete peace of mind.