The Next Generation of Mouse Model Preparation Platform
- 4-Week Delivery: World’s fastest custom mouse model development.
- TurboMice™ Tech: Proprietary high-efficiency gene-editing platform.
- Full Capabilities: Expert conditional knockouts, knock-ins, and humanized models.
- Validated Quality: Guaranteed high precision and model viability.
Why VeloGene?
Mouse Customize & Embryonic Stem Cell Bank
VeloGene Biotechnology Mouse Customize Service
TurboMice™ technology can shorten the mouse model customize cycle to as short as 2 months, with the first generation mice being 100% purebred, eliminating the need for breeding and selection.
TurboMice™ Knock Out
- Rapid Delivery: Obtain 100% targeted, fully genotyped homozygous knockout F0 experimental mice in just 3–5 months, drastically cutting down the traditional 6–12 month timeline.
- Streamlined Workflow: Entirely bypasses chimeras, germline transmission verification, and guesswork-style mating by leveraging direct embryo-level production from edited stem cells.
- Complex Customization: Supports advanced scenarios including large-fragment deletions (>20 kb), multi-gene knockout arrays, conditional knockout (Flox) designs, and complex mutation combinations.
- Strain & Value Advantages: Eliminates multi-generation intercrossing genetic drift with identical clone-level uniformity, and includes 2 years of free ESC cryopreservation and banking for easy 2-month batch re-ordering.
TurboMice™ Conditional Knock Out
VeloGene’s TurboMice™ CKO service revolutionizes traditional conditional knockout model generation by combining embryonic stem cell (ESC) editing with tetraploid complementation technology. By integrating loxP sites and tissue-specific Cre elements at the ESC stage, the platform bypasses prolonged breeding cycles and chimera production to deliver ready-to-use cohorts efficiently.
- Rapid Delivery: Obtain 100% targeted, fully genotyped Cre+/flox homozygous F0 experimental mice in just 4–6 months, drastically cutting down the traditional 12–18 month timeline.
- Streamlined Workflow: Entirely bypasses chimeras, germline transmission verification, and guesswork-style mating by leveraging direct embryo-level production from edited stem cells.
- Complex Customization: Supports advanced scenarios including single-chromosome multiplex editing, multi-gene conditional knockouts, large-fragment humanization, and inducible CreERT2 systems.
- Strain & Value Advantages: Eliminates multi-generation intercrossing genetic drift with identical clone-level uniformity, and includes 2 years of free ESC cryopreservation and banking for easy cohort expansion.
TurboMice™ Knock In
VeloGene’s TurboMice™ Knock-in service revolutionizes traditional knock-in mouse model generation by combining embryonic stem cell (ESC) editing with tetraploid complementation technology. By executing precise in-situ gene modification and multi-locus insertion at the ESC stage, the platform bypasses prolonged multi-generational breeding and chimera production to deliver ready-to-use cohorts efficiently.
- Rapid Delivery: Obtain 100% targeted, fully genotyped homozygous knock-in F0 experimental mice in just 3–5 months, drastically cutting down the traditional 6–12 month timeline.
- Streamlined Workflow: Entirely bypasses chimeras, germline transmission verification, and guesswork-style mating by leveraging direct embryo-level production from edited stem cells.
- Complex Customization: Supports advanced scenarios including large-fragment insertions (>10 kb to >50 kb), multi-locus gene combinations, reporter genes, tag proteins, humanized sequences/functional domains, and conditional knockout (Flox) designs.
- Strain & Value Advantages: Eliminates multi-generation intercrossing genetic drift with identical clone-level uniformity, and includes 2 years of free ESC cryopreservation and banking for easy 2-month batch re-ordering.
TurboMice™ Humanization
VeloGene’s TurboMice™ Humanization service revolutionizes traditional humanized mouse model generation by combining embryonic stem cell (ESC) editing with tetraploid complementation technology. By executing precise in-situ humanization and multi-locus replacement at the ESC stage, the platform bypasses prolonged multi-generational breeding and chimera production to deliver ready-to-use cohorts efficiently.
- Rapid Delivery: Obtain 100% targeted, fully genotyped homozygous humanized F0 experimental mice in just 3–5 months, drastically cutting down the traditional 6–12 month timeline.
- Streamlined Workflow: Entirely bypasses chimeras, germline transmission verification, and guesswork-style mating by leveraging direct embryo-level production from edited stem cells.
- Complex Customization: Supports advanced scenarios including large-fragment humanization (>20 kb), multi-gene humanization arrays, functional domain replacements, and point mutation combinations.
- Strain & Value Advantages: Eliminates multi-generation intercrossing genetic drift with identical clone-level uniformity, and includes 2 years of free ESC cryopreservation and banking for easy 2-month batch re-ordering.
TurboMice™ Point Mutation
VeloGene’s TurboMice™ Point Mutation service revolutionizes traditional point mutation mouse model generation by combining embryonic stem cell (ESC) editing with tetraploid complementation technology. By executing precise in-situ single nucleotide variations (SNVs), small insertions/deletions (InDels), or missense/nonsense mutations at the ESC stage, the platform bypasses prolonged multi-generational breeding and chimera production to deliver ready-to-use cohorts efficiently.
- Rapid Delivery: Obtain 100% targeted, fully genotyped homozygous point mutation F0 experimental mice in just 3–5 months, drastically cutting down the traditional 6–12 month timeline.
- Streamlined Workflow: Entirely bypasses chimeras, germline transmission verification, and guesswork-style mating by leveraging direct embryo-level production from edited stem cells.
- Complex Customization: Supports advanced scenarios including human genetic disease-causing loci simulations, protein functional domain key-site mutations, same-gene multi-site combination mutations, and nonsense mutations/premature termination codon introductions.
- Strain & Value Advantages: Eliminates multi-generation intercrossing genetic drift with identical clone-level uniformity, and includes 2 years of free ESC cryopreservation and banking for easy 2-month batch re-ordering.
TurboMice™ Transgenic
- Rapid Delivery: Obtain 100% targeted, fully genotyped homozygous transgenic F0 experimental mice in just 3–5 months, drastically cutting down the traditional 6–12 month timeline.
- Streamlined Workflow: Entirely bypasses chimeras, germline transmission verification, and guesswork-style mating by leveraging direct embryo-level production from edited stem cells.
- Complex Customization: Supports advanced scenarios including large-fragment functional gene overexpression (>20 kb), multi-gene array/complex structure construction, reporter gene knock-in, and conditional transgenic models.
- Strain & Value Advantages: Eliminates multi-generation intercrossing genetic drift with identical clone-level uniformity, and includes 2 years of free ESC cryopreservation and banking for easy 2-month batch re-ordering.”
TurboMice™ Multi-Side Gene Editing
- Homozygous mice: 4~6 months
- 4Rs benefit: no chimeras, no breeding selection required
VeloGene Biotechnology Embryonic Stem Cell Bank
High Nourishing Capacity
Improved Predictability
Efficient Drug Screening and Development
In-depth Genetic Research
IP Assurance
At VeloGene, we operate on a strict fee-for-service model. All intellectual property (IP) and materials created for your project are 100% yours. We take every measure to safeguard your IP, ensuring no vectors, ES cells, or mouse lines are retained or resold to third parties. This way, you can focus on your research with complete peace of mind.